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Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies 1st edition
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Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies
Research focused on protein folding, misfolding, and aggregation is leading to major advances across biochemistry and medicine. The elucidation of a folding code is proving to be of extreme importance in the postgenomic era, where a number of orphan genes have been identified for which no clear function has yet been established. This research is starting to shed light on the molecular and biochemical basis of a number of neurodegenerative diseases of dramatic impact.
Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies addresses key issues concerning protein misfolding and aggregation in neurodegenerative diseases. Building on recent developments, including the recognition of protein misfolding as both a marker and a causal agent, the text presents the work of those who are actively pursuing more effective treatments, as well as preventative measures, and a possible cure. These include the use of molecular chaperones to control misfolding and novel pharmaceuticals, as well as the potential role of various inhibitors and NSAIDS.
A Comprehensive Multifaceted Examination of the Complex Causal Agents Implicated in Protein Misfolding
Divided into five sections, this groundbreaking text provides up-to-date accounts for Alzheimer?s, Parkinson?s, Huntington?s, Amyotrophic Lateral Sclerosis and Transmissible Spongiform Encephalitis. It also explores the highly likelihood that multiple factors, including oxidative stress, play a role in these complex diseases.
592 pages
| Media | Books Paperback Book (Book with soft cover and glued back) |
| Released | October 18, 2019 |
| ISBN13 | 9780367388126 |
| Publishers | Taylor & Francis Ltd |
| Pages | 596 |
| Dimensions | 150 × 220 × 10 mm · 453 g |
| Language | English |
| Editor | Sewell, Robert D. E. |
