Regulation of Carcinogenesis, Angiogenesis and Metastasis by the Proprotein Convertases (PC's): A New Potential Strategy in Cancer Therapy - A-majid Khatib - Books - Springer-Verlag New York Inc. - 9781402047930 - August 9, 2006
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A-majid Khatib
Regulation of Carcinogenesis, Angiogenesis and Metastasis by the Proprotein Convertases (PC's): A New Potential Strategy in Cancer Therapy 2006 edition

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Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. Each chapter discusses the importance of the convertases in the activation of various cancer-related molecules including growth factors, adhesion molecules and proteases.

Marc Notes: Includes bibliographical references and index. Table of Contents: Preface / Abdel-Majid Khatib -- List of Contributors -- Introduction / Nabil G. Seidah -- Chapter 1. Discovery of the Proprotein Convertases and their Inhibitors / Abdel-Majid Khatib, Nathalie Scamuffa, Fabien Calvo, Michel Chretien, Nabil G. Seidah -- Chapter 2. Signalling Pathways Leading to Furin Expression in Cancer / Stephanie McMahon, Claire M. Dubois -- Chapter 3. PACE4 Gene Expression in Human Ovarian Cancer / Brigitte L. Theriault, Yangxin Fu, Shawn K. Murray, Mark W. Nachtigal -- Chapter 4. Proprotein Convertases in Tumorigenesis, Angiogenesis and Metastasis / Geraldine Siegfried, Michel Chretien, Abdel-Majid Khatib -- Chapter 5. Proprotein Convertases, Metalloproteases and Tumor Cell Invasion / Daniel E. Bassi, Andres J. P. Klein-Szanto -- Chapter 6. Modulation of Integrin Function by Endoproteolytic Processing: Role in Tumour Progression / Rigot V, Luis J. -- Chapter 7. Growth Factors: To Cleave or Not to Cleave / Abdel-Majid Khatib, Siegfried Geraldine -- Chapter 8. Evaluation of Anti-Proprotein Convertase Activity of Diterpene Andrographolid Derived Products / Ajoy Basak, Upendra K. Banik, Sarmistha Basak, Nabil G. Seidah, Suiyang Li -- Index.

Media Books     Hardcover Book   (Book with hard spine and cover)
Released August 9, 2006
ISBN13 9781402047930
Publishers Springer-Verlag New York Inc.
Pages 157
Dimensions 210 × 297 × 11 mm   ·   430 g
Editor Khatib, Abdel-Majid

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