PAS Proteins: Regulators and Sensors of Development and Physiology - Stephen T Crews - Books - Springer-Verlag New York Inc. - 9781402075865 - September 30, 2003
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Stephen T Crews
PAS Proteins: Regulators and Sensors of Development and Physiology 2003 edition

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PAS proteins control numerous physiological and developmental events, and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen, and energy status.

Marc Notes: Includes bibliographical references and index. Table of Contents: Structure of the PAS Fold and Signal Transduction Mechanisms.- Signal Transduction in Prokaryotic PAS Domains.- bHLH-PAS Proteins in C. elegans.- Drosophila bHLH-PAS Developmental Regulatory Proteins.- Methoprene-Tolerant, a PAS Gene Critical for Juvenile Hormone Signaling in Drosophila Melanogaster.- The P160 Family of Steroid Hormone Receptor Coactivators.- The Ah Receptor.- The HIF-1 Family of bHLH-PAS Proteins: Master Regulators of Oxygen Homeostasis.- Hormones, Obesity, Learning, and Breathing The Many Functions of Mammalian Single-Minded Genes.- PAS Proteins in the Mammalian Circadian Clock."Publisher Marketing: This volume provides a comprehensive examination of the biochemistry and biology of all classes of known PAS proteins, with the intention that readers will find insight into their own work and ideas from study of the multitude of PAS protein functions. PAS proteins control numerous physiological and developmental events and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen and energy status. Not surprising, given these roles, there is intense investigation of the roles of bHLH-PAS proteins in issues of human health including: (1) cancer induction, (2) cancer growth and vascularity, (3) birth defects, including Down syndrome, (4) appetite control and obesity, (5) sleep rhythm disorders and (6) mental health disorders such as social interactions and learning.

Media Books     Hardcover Book   (Book with hard spine and cover)
Released September 30, 2003
ISBN13 9781402075865
Publishers Springer-Verlag New York Inc.
Pages 263
Dimensions 155 × 235 × 20 mm   ·   594 g
Language English  
Editor Crews, Stephen T.

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