Ekaterina E. Heldwein

Alphaherpesviruses Ekaterina E. Heldwein

Our understanding of the alphaherpesviruses has significantly advanced creating the need for this new book that distils the most important new information to provide a timely overview. Chapters are written by well-respected researchers, each offering their perspectives on the current state of the field, using herpes simplex virus as the main focus. Topics covered include: genomics; entry into the cell; genome delivery from the cell periphery to the nucleus; the fate of the genome in the nucleus; infection of neurons; establishment of latency; host cellular responses to infection; viral immune evasion strategies; capsid egress from the nucleus; virion assembly in the cytoplasm; vaccines; oncolytic vectors. This book is essential reading for students, virologists, immunologists, medical and veterinary professionals and scientists working on neuroinvasive alphaherpesviruses. It is also a recommended reading for anyone with an interest in neurovirology and persistent viral infections.