Cell Immortalization - Progress in Molecular and Subcellular Biology - Alvaro Macieira-coelho - Books - Springer-Verlag Berlin and Heidelberg Gm - 9783642084911 - December 4, 2010
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Alvaro Macieira-coelho
Cell Immortalization - Progress in Molecular and Subcellular Biology Softcover reprint of hardcover 1st ed. 2000 edition

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Jacket Description/Back: This book describes the most outstanding theoretical hypotheses aiming at explaining the infinite proliferative potential of a cell population, what is now known under the term cell immortalization. It elucidates the phenomenon from an evolutionary point of view, and describes the cell systems used and the experiments performed at the cellular and molecular levels to determine the mechanisms responsible for this cell property. It also appraises how the mortal and immortal phenotypes reflect characteristics of the respective organism, and stresses how this goes beyond the proposal that its opposite, the mortal phenotype, is a mechanism to protect the organism against cancer. Table of Contents: A Theory on Cellular Aging and Cell Immortalization.- Cell Immortality: Maintenance of Cell Division Potential.- Comparative Biology of Cell Immortalization.- Clonal Life Cycle of Paramecium in the Context of Evolutionary Acquired Mortality.- Cellular Genealogy of In-Vitro Senescence and Immortalization.- SV40-Mediated Immortalization.- Concepts of Immortalization in Human Mammary Epithelial Cells.- Telomeres and Cell Division Potential.- Cellular mortality and Immortalization: A Complex Interplay of Multiple Gene Functions. Marc Notes: Originally published: 2000.; This text describes the most outstanding theoretical hypotheses aiming at explaining the infinite proliferative potential of a cell population, what is now known under the term cell immortalization.

216 pages, 10 black & white illustrations, 2 black & white tables, biography

Media Books     Paperback Book   (Book with soft cover and glued back)
Released December 4, 2010
ISBN13 9783642084911
Publishers Springer-Verlag Berlin and Heidelberg Gm
Pages 208
Dimensions 155 × 235 × 11 mm   ·   308 g
Language German  
Editor Macieira-Coelho, Alvaro

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