Irina Zhuravleva

Gemosovmestimost' Kardiovaskulyarnykh Bioprotezov - Problemy I Resheniya: Novye Podkhody K Povysheniyu Gemosovmestimosti Biologicheskikh Protezov Dlya Serdechno-sosudistoy Khirurgii Irina Zhuravleva Russian edition

Razrabotka protezov dlya zameshcheniya porazhennykh klapanov serdtsa i sosudov yavlyaetsya aktual'nym napravleniem razvitiya serdechno-sosudistoy khirurgii. Dlya protezov, nakhodyashchikhsya v postoyannom kontakte s krov'yu i podverzhennykh vysokomu risku tromboza, naibolee vazhnym svoystvom yavlyaetsya gemosovmestimost'. Biologicheskie protezy imeyut nekotorye preimushchestva pered sinteticheskimi analogami ? udovletvoritel'nye gemodinamicheskie parametry, tromborezistentnost', ustoychivost' k infektsii. Odnako analiz otdalennykh rezul'tatov primeneniya sosudistykh bioprotezov svidetel'stvuet, chto v strukture oslozhneniy preobladayut trombozy. Dlya klapanov serdtsa i zaplat dlya intrakardial'noy i angioplastiki problema trombozov i tromboemboliy ne stol'ko sushchestvenna, no, tem ne menee, dannye protezy nuzhdayutsya v povyshenii gemosovmestimosti. Takim obrazom, na rezul'taty operatsiy okazyvaet vliyanie kachestvo bioprotezov, kotoroe vo mnogom zavisit ot sposoba konservatsii i posleduyushchey modifikatsii biomateriala. Dannaya rabota posvyashchena izucheniyu vliyaniya novykh konservantov klassa epoksisoedineniy i razlichnykh antikoagulyantov na gemosovmestimost' kardiovaskulyarnykh bioprotezov.