Differentsial'noe Metilirovanie Genomov: Analiz Metodami Nepredvzyatogo Skrininga - Vladimir Strel'nikov - Books - LAP LAMBERT Academic Publishing - 9783659514524 - January 11, 2014
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Vladimir Strel'nikov
Differentsial'noe Metilirovanie Genomov: Analiz Metodami Nepredvzyatogo Skrininga Russian edition

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V monografii opisan printsipial'no novyy sovremennyy algoritm skrininga differentsial'nogo metilirovanniya genomov, osnovannyy na sochetanii klassicheskogo gennoinzhenernogo podkhoda ? amplifikatsii intermetilirovannykh saytov (AIMS), vysokorazreshayushchego sposoba razdeleniya fragmentov nukleinovykh kislot ? kapillyarnom elektroforeze, i original'nogo komp'yuternogo obespecheniya. Razrabotannyy sposob opredeleniya genomnoy prinadlezhnosti vyyavlyaemykh differentsial'no metilirovannykh fragmentov DNK isklyuchaet neobkhodimost' ikh reamplifikatsii, klonirovaniya i sekvenirovaniya. Vyyavlennye pri analize genomov kletochnykh liniy raka molochnoy zhelezy ZR-75-1, HBL-100, HS 578 T, BT-474, MCF7 i T-47D differentsial'no metilirovannye genomnye lokusy mogut sluzhit' substratom dlya razrabotki molekulyarno-geneticheskikh markerov raka molochnoy zhelezy.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released January 11, 2014
ISBN13 9783659514524
Publishers LAP LAMBERT Academic Publishing
Pages 160
Dimensions 150 × 9 × 226 mm   ·   256 g
Language German  

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