Telomernyy Mekhanizm Stareniya: Obzor - Irina Gamaley - Books - Palmarium Academic Publishing - 9783659986574 - July 17, 2013
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Irina Gamaley
Telomernyy Mekhanizm Stareniya: Obzor Russian edition

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Izvestno, chto maksimal'naya prodolzhitel'nost' zhizni cheloveka ogranichena i sostavlyaet poryadka 100 let. Naibolee logichnym kandidatom na rol' regulyatora, opredelyayushchego prodolzhitel'nosti zhizni cheloveka, yavlyaetsya dlina telomer khromosom. Privodyatsya ob"yasneniya togo, kakim obrazom ukorochenie telomer mozhet byt' prichinoy stareniya i ogranicheniya prodolzhitel'nosti zhizni. Pokazana nesposobnost' okislitel'noy teorii stareniya ob"yasnit' mnozhestvo besspornykh faktov, legko ob"yasnyaemykh v ramkakh telomernoy teorii, takikh kak neogranichennaya proliferatsiya zlokachestvennykh kletok, a takzhe togo, pochemu novorozhdennye deti nachinayut staret' kazhdyy raz s nulya, a ne s urovnya, dostignutogo kletkami roditeley k momentu zachatiya. Postuliruetsya, chto dazhe esli okislitel'nye povrezhdeniya polnost'yu otsutstvuyut, telomery, tem ne menee, ukorachivayutsya s kazhdym mitoticheskim tsiklom, potomu chto tak ustroen mekhanizm replikatsii DNK, i starenie progressiruet ? imenno eto my nablyudaem pri deystvii lyubykh antioksidantov. No esli telomery ne ukorachivayutsya, chto imeet mesto v transformirovannykh kletkakh, gde aktivna telomeraza, starenie ostanavlivaetsya i transformirovannye kletki deystvitel'no ne stareyut.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released July 17, 2013
ISBN13 9783659986574
Publishers Palmarium Academic Publishing
Pages 96
Dimensions 150 × 6 × 225 mm   ·   161 g
Language German  

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