Sergey Menzikov

Atr-zavisimaya Sl-transportnaya Sistema Neyronal'nykh Membran Sergey Menzikov Russian edition

Materialy, predstavlennye v knige, kasayutsya odnoy iz aktual'neyshikh zadach neyrokhimii ? vyyavleniyu v nervnoy tkani spetsificheskikh protsessov, trebuyushchikh energeticheskikh zatrat. Gipoteza o sushchestvovanii v neyronal'nykh membranakh ATRazy, sopryazhennoy s GAMKa-retseptorami, byla vyskazana bolee dvukh desyatiletiy nazad. Avtorom podrobno opisany svoystva obnaruzhennoy im v neyronal'nykh membranakh mozga i obonyatel'noy vystilke ATR-zavisimoy Cl-transportiruyushchey sistemy, sopryazhennoy s GAMKa-retseptorami, izuchenie kotoroy provodilos' na kletochnom, molekulyarnom i funktsional'nom urovnyakh. Privedennye dannye otkryvayut perspektivu dlya dal'neyshikh issledovaniy molekulyarnykh svoystv obnaruzhennogo Cl-nasosa v norme i pri patologii. V obzornoy chasti knigi rassmotreny razlichnye Cl-transportnye sistemy neyronal'nykh membran. Osoboe vnimanie udeleno mekhanizmam, kotorye uchastvuyut v transporte ionov khlora protiv elektrokhimicheskogo gradienta, tormoznym retseptoram, netipichnomu povedeniyu ikh funktsional'noy aktivnosti i roli ATF v etikh protsessakh. Kniga prednaznachena dlya neyrokhimikov, neyrofiziologov, nevropatologov, farmakologov, a takzhe dlya studentov biologicheskikh i meditsinskikh fakul'tetov universitetov.